The article discussed about that how low levels of miconutrient cause viral infections and show averse cliniccal outcomes .To maximize the nutritional defense against infections , a daily allowance of vitamins and trace elements for malnourished patients at risk or diadnosed with COVID-19 must be beneficial. recent studies have shown that vitamin D and selenium defencies are evident in patients with acute respiratory tract infections . vitamin D helps and stimulates the production of antimicrobial peptides. helps in preventing cytokine storms by decreasing the production of inflammatory cytokines. selenium helps in cytotoxic effector cells as per the studies.