The article summarises1-Role of specific nutrients (micronutrients) in supporting immune system, particularly, but not exclusively, with regard to antiviral defences.2-Roles of nutrition in overcoming abnormal gut microbiota, termed dysbiosis and and in calming a so-called ‘cytokine storm’, The article talks about importance of immune system in protecting the host from pathogenic organisms, which is always active, shows enhanced activity during infection, accompanied by an increased rate of metabolism, requiring energy sources, substrates for biosynthesis and regulatory molecules, which are all ultimately derived from the diet.-Obesity can be associated with loss of immune competence having increased susceptibility to a range of bacterial, viral and fungal infections and poorer responses to vaccination.-A healthy gut microbiota is believed to play a role in host immune defence by creating a barrier against colonisation by pathogensGood nutrition creates an environment in which the immune system is able to respond appropriately to challenge, irrespective of the nature of the challenge. Consuming a diet of diverse would be best in supporting immune system, both macromolecules and various micronutrients are needed to optimally support the immune system can easily be achieved through diet alone and supplementation might be considered in deficiency.